B.S. in Biotechnology
Wenzhou University, Wenzhou, China

MRes. in Molecular Bioscience
University of Liverpool, Liverpool, UK

Ph.D. in Life Science (Biology and Biochemistry)
Universiti Malaya, Kuala Lumpur, Malaysia.

Principles of Biology (Laboratory)

Cell Physiology (Laboratory)

Dr. Tian earned his Ph.D. in Life Science from Universiti Malaya and a master’s degree in Molecular Bioscience from the University of Liverpool. Tian is the founder of the Natural Science Laboratory at Wenzhou-Kean University, the head of the Lab Center, the Office Director of the Zhejiang Bioinformatics International Science and Technology Cooperation Center and the Wenzhou Municipal Key Laboratory for Applied Biomedical and Biopharmaceutical Informatics. Additionally, he is the Deputy Director of the Provincial Biotechnology Experimental Teaching Demonstration Center at Wenzhou-Kean University. Tian holds memberships in several prestigious international and national societies, including the Royal Society of Biology (RSB, UK), Sigma Xi Scientific Research Honor Society, Bergey’s International Society for Microbial Systematics (BISMiS), and the International Pangolin Research Consortium. As the principal investigator or key member, Tian has led or participated in over 20 national, provincial, municipal, and university-level research projects, with total funding exceeding 4 million RMB. He has published nearly 30 high-impact papers in internationally renowned journals, including Nature Plants, Molecular Plant, BMC Biology, and BMC Genomics, and holds eight granted invention patents. Dr. Tian’s outstanding performance and exceptional achievements have earned him numerous honors at the provincial, municipal, and university levels, showcasing his leadership and influence in scientific research and laboratory innovation.

WORK EXPERIENCE

Senior Head of the Lab Center, CSMT ------------------------ 07/2024 to present

Head of the Lab Center, CSMT ------------------------------- 12/2023 to 07/2024

Coordinator for the Lab & Research Center ----------------- 10/2020 to 12/2023

Lab Manager for the Office of Academic Affairs ----------- 02/2017-10/2020

Staff for the Office of Academic Affairs ---------------------- 06/2015-02/2017

AWARDS

Individual awards:

• Second Prize for Outstanding Presentation by a Young Committee Member, Bioinformatics Society of Zhejiang Province, 12/2024
• Outstanding Contribution Award for the 10th Anniversary, Wenzhou-Kean University (￥13,000), 09/2024
• Bergey's International Society for Microbial Systematics (BISIMiS) International Student Academic Travel Award ($1,000), 11/2023
• Advanced Individual in Laboratory Work in Higher Education Institutions, Zhejiang Province, Laboratory Management Society of Zhejiang Province, 03/2023
• Outstanding Staff, Wenzhou-Kean University, 03/2023
• Outstanding Staff, Wenzhou-Kean University, 03/2022
• The Award for Excellence in Management in the Academic Year 2020-2021 (￥5,000), Wenzhou-Kean University, 09/2021
• An outstanding member of the Communist Party of China, Wenzhou-Kean University, 07/2021
• Ten Thousand Good Party Members Honor Title in Zhejiang Province, 11/2018
• Advanced Individual, Wenzhou-Kean University, 02/2018
• Outstanding Campus Life Advisor (CLA), Wenzhou-Kean University, 02/2018
• Outstanding Staff, Wenzhou-Kean University, 02/2018
• Outstanding Staff, Wenzhou-Kean University, 01/2017
• The Second-Class Scholarship, Wenzhou University, 11/2014
• The Outstanding Student, Wenzhou University, 11/2014
• The National Grants, China Government, 2014
• The Outstanding Student, Wenzhou University, 05/2014
• Advanced Individual in Summer Social Practice, Zhejiang Province, 11/2013
• Outstanding Student Leader, Wenzhou University, 10/2013
• The Third Prize in Biology Skill Competition, Wenzhou University, 06/2013
• Advanced Individual, Wenzhou University, 12/2012
• The Third-Class Scholarship, Wenzhou University, 12/2012
• The Self-improvement Star, Wenzhou University, 12/2012
• The Third-Class Scholarship, Wenzhou University, 05/2012
• Top Ten Singer, Wenzhou University, 11/2011

Team awards:

• Wenzhou-Kean University Excellent Team Award for Comprehensive Assessment in Admission Work to Lab Center (￥37,000), 09/2024
• Excellent Paper Award for Young Science and Technology Workers in Zhejiang Province, 01/2024
• Wenzhou-Kean University Excellent Team Award for Comprehensive Assessment in Admission Work to Lab Center (￥40,000), 09/2022
• Wenzhou-Kean University Advanced Team Award for Research and Educational Innovation to the Key Lab Team (￥5,000), 09/2022
• Wenzhou-Kean University Advanced Team Award for Teaching and Education to the Office of Academic Affairs (￥5,000), 09/2022

RESEARCH GRANTS

1. Department of Education of Zhejiang Province, General Program, Wenkendafa [2024] No.55, Research on the Mechanism by Which Gut Microbiota Modulate Host Metabolism to Promote the Development of Colorectal Cancer, 2024-2026, Funding: 10,000 RMB, Ongoing, Principal Investigator.
2. Agricultural and Rural Affairs Bureau of Yongjia County, Wenzhou, Industrial Promotion Project of the Modern Agriculture Research Institute, Project No. 2024YJ005, Research on the Hepatoprotective Mechanism of Yongjia's Specialty Medicinal Herb Gardenia jasminoides and Its Product Development and Demonstration, 2024, Funding: 100,000 RMB, Ongoing, Key Member.
3. Wenzhou Science and Technology Bureau, Basic Scientific Research Project, Wenkeguan [2024] No.9, Structural Characterization of Gardenia Polysaccharides and Their Mechanisms in Regulating the Gut-Liver Metabolic Axis to Alleviate Oxidative Liver Damage in Diabetes, 2024-2026, Funding: 3,0000 RMB, Ongoing, Co-Investigator.
4. Research Project on Laboratory Work in Zhejiang Province Universities, YB202226, Development of Laboratory Safety Management System in Sino-Foreign Cooperative Universities Based on EHS Principles, 2022-2024, Funding: 3,000 RMB, Ongoing, Co-Investigator.
5. China Resources Shenzhen International Trust (CRSIT): Tengger Desert Environmental Charity Trust, Horizontal Sponsorship Project, Huarun [2021] Charity Funding No. 1, Conservation of Biodiversity and Endangered Species in the Yellow River, 2022-2023. Funding: 400,000 RMB, Completed, Key Member.
6. China Railway Trust: Mingde No.1 Yihua Environmental Protection Charity Trust, Horizontal Sponsorship Project, Zhongtie [2021] Charity Funding Nos. 1-6, Research and Conservation of Pangolin, a National Grade I Protected Animal, 2021-2022. Funding: 500,000 RMB, Completed, Key Member.
7. Wenzhou Science and Technology Bureau, Key Lab Program, Wenke Jiji [2021] No.4, Wenzhou Municipal Key Laboratory for Applied Biomedical and Biopharmaceutical Informatics, 2021.09-2023.09. Funding: 800,000 RMB, Ongoing, Key Member (Office Director).
8. Zhejiang Provincial Science and Technology Department, International Science and Technology Cooperation Carrier Project, Zheke Fawai [2020] No.62, Zhejiang Bioinformatics International Science and Technology Cooperation Center, 2020. Funding: 1,000,000 RMB, Completed, Key Member (Office Director).
9. National Natural Science Foundation of China, Youth Project, Project No: 32100581, CryptoSignals: unraveling the signaling roles of cryptic moonlighting sites in complex proteins, 2022.01-2024.12. Funding: 300,000 RMB, Ongoing, Co-Investigator.
10. Wenzhou-Kean University Student Partnering with Faculty/Staff Research Program, Project No: SpS2021030, Study on the effect and underlying mechanism of human interferon combination in cervical cancer cells. 2021-2022. Funding: 21,000 RMB, Completed, Principal Investigator.
11. Wenzhou-Kean University Student Partnering with Faculty/Staff Research Program, Project No: SpS2021030, Developing novel recombination technology for human interferon-epsilon. 2021-2022. Funding: 20,000 RMB, Completed, Principal Investigator.
12. Wenzhou Ouhai District Development and Reform Advisory Committee, Project No: ZXW20200415015, Research on Actively Harnessing Resources from the World Young Scientists Summit for the Transformation and Implementation of Scientific and Technological Innovations. 06/2020-12/2020, Funding: 20,000 RMB, Completed, Co-Investigator.
13. National Natural Science Foundation of China, International (regional) cooperation and exchange programs, Project No: 31850410470, Towards a highly tailored indoor horticulture: A functional genomics guided phenotypic approach, 01/2019-12/2020. Funding: 399,600 RMB, Completed, Co-Investigator.
14. Zhejiang Province Natural Science Foundation Project, Youth Project, Project No: LQ19C130001, Towards a highly tailored indoor horticulture: A functional genomics guided phenotypic approach. 01/2019-12/2021. Funding: 90,000 RMB, Completed, Key Member.
15. National Natural Science Foundation of China, Project No: 81703410, Mechanism of a novel and efficient in-trans drug carrier K16ApoE across the blood-brain barrier, 01/2018-12/2020. Funding: 190,000 RMB, Completed, Co-Investigator.
16. Wenzhou Science and Technology Project, Project No: Y20170019, Construction of chimeras of peptide K16ApoE and lysosomal enzyme TPP1 and their efficacy in crossing the blood-brain barrier, 01/2018-12/2019. Funding: 20,000 RMB, Completed, Co-Investigator:
17. Wenzhou-Kean University Student Partnering with Staff (Sps) research program, Project No: WKU201718051, Study on Cosmetic Effect of Akebia Fruit Extract, 03/2018-03/2019. Funding: 30,000 RMB, Completed, Co-Investigator.
18. Wenzhou-Kean University Student Partnering with Staff (Sps) research program, Project No: WKU201718050, The construction feasibility study of “Sponge University” Project in Wenzhou-Kean University: Based on the Study in Changes of Water Flow and Water Quality on Campus in Certain Time Period, 03/2018-03/2019. Funding: 21,800 RMB, Completed, Co-Investigator.
19. Zhejiang Province Natural Science Foundation Regular Project, Project No: LY16H080008, Crossing the blood-brain barrier: the mechanism and application of a novel and effective peptide-mediated drug delivery system in central nervous system leukemia, 01/2016-12/2018. Funding: 80,000 RMB, Completed, Co-Investigator.
20. Wenzhou Public Welfare Research Project, Tuan Wen Chuan [2017] No.7, The Evaluation Project of Comprehensive Improvement in Wen-Rui Tang River, 05/2017-12/2017. Funding: 20,000 RMB, Completed, Principal Investigator.
21. Wenzhou Education Bureau Experimental Teaching Demonstration Center Project, Wen Jiao Gao Han [2015] No.75, Bio Experimental Teaching Demonstration Center of Wenzhou-Kean University, 07/2015-07/2018. Funding: 300,000 RMB, Completed, Principal Investigator.

PATENTS

1. Choo, Siew Who; Tian, Xuechen, A Combination Drug of Human Interferon-ε and Interferon-γ, 2020-03-31, China, 202010241103.2, Granted.
2. Choo, Siew Who; Tian, Xuechen, Application of Human Interferon-epsilon in Tumor Therapy, 2020-03-31, China, 202020140579.4.
3. Choo, Siew Who; Tian, Xuechen, A Combination Drug of Human Interferon-ε and Interferon-γ, 2021-05-07, Australian, 2021102398, Granted.
4. Choo, Siew Woh; Lin, Haojie; Lin, Zhengyi; Zhao, Haiyi; Tian, Xuechen, An anti-inflammatory polypeptide and corresponding synthesizing method, 2021-06-04, China, 202110622991.7, Granted.
5. Choo, Siew Woh; Chen, Li; Song, Lanni; Tian, Xuechen, An Anticancer Bioactive Peptide and a Synthesis Method Thereof, 2021-06-04, China, 202110623109.0, Granted.
6. Choo, Siew Woh; Chen, Li; Song, Lanni; Song, Kunping; Tian, Xuechen, A composition and antibacterial application thereof, 2021-10-13, China, 202111195294.4, Granted.
7. Choo, Siew Woh; Chen, Li; Song, Lanni; Song, Kunping; Tian, Xuechen, A Bioactive Peptide and Its Synthesis Method, 2021-08-18, Australian, 2021105757, Granted.
8. Choo, Siew Woh; Lin, Haojie; Lin, Zhengyi; Zhao, Haiyi; Tian, Xuechen, An anti-inflammatory polypeptide and corresponding synthesizing method, 2021-07-20, Australian, 2021104341, Granted.
9. Choo, Siew Woh; Chen, Li; Song, Lanni; Song, Kunping; Tian, Xuechen, Composition and antibacterial usage thereof, 2022, Germany, LU102887, Granted.
10. Yan, Qingying; Li, Lanxing; Dong, Linyinxue; Tian, Xuechen; Yang, Yixin, A Dye Specifically Formulated for Plastics，2023-05-22, China, 202310575223.X.

CONFERENCES

Oral Presentation:

1. Academic Seminar (Online) of Universiti Malaya. Kula Lumpur, Malaysia, Feb 4, 2021

Title: Comparative Sequencing and Analysis of Oral Actinomyces Species

2. Wenzhou University Thematic Education, Wenzhou, Zhejiang, China, Nov 29, 2022

Title: My Story with the Biotechnology Major: Future Prospect

3. The 5th Bergey's International Symposium on Systematic Microbiology, Guangzhou, Guangdong China, Nov 6, 2023

Title: Genomic Characterization and Comparative Analysis of Schaalia dentiphila sp. nov. and Schaalia dentiphila subsp. caries. subsp. nov.

4. The 28th Biological Science Graduate Conference (BSGC), Kuala Lumpur, Malaysia, Dec 14, 2023

Title: Genome-Based Characterization and Comparative Analysis of Oral Actinomyces Species

5. Academic Lecture of Wenzhou-Kean University, Wenzhou, Zhejiang, China, May 14, 2024

Title: Innovative Research Across Life Sciences: Spotlight on Microbiology, Animal Studies, Cancer Research, and Agrotechnology.

6. 2024 International Forum of Microbes and One Health & Annual Meeting of Guizhou Microbiological Society, Guiyang, Guizhou, China, Dec 6, 2024.

Title: Genome Characterization and Taxonomy of Oral Actinomyces-Like Species

7. The 11th Annual Academic Conference of Zhejiang Bioinformatics Society & Academic Conference on Innovative Integration of Bioinformatics and Computer Science – Youth Forum, Hangzhou, Zhejiang, China, Dec 28, 2024.

Title: Application of Comparative Genome Sequencing and Analysis in Identifying Novel Microorganisms

Posters:

• Yuxin Deng, Jiaqi Zhang, Ming Xie, Haohong Tu, Kunping Song/Choo Siew Who* &Tian Xuechen*, Study on the effect and underlying mechanism of human interferon combination in cervical cancer cells. Research Day Activities, Wenzhou-Kean University.
• Geok Yuan Annie Tan^*, Xuechen Tian^*, Wee Fei Aaron Teo, Siew Woh Choo, and Nicholas S. Jakubovics, Genome characterization and taxonomy of Actinomyces acetigenes sp. nov., and Actinomyces stomatis sp. nov. The 5th Bergey's International Symposium on Systematic Microbiology, Guangzhou, China, November 6^th, 2023.

PROFESSIONAL MEMBERSHIPS

• Member of Sigma Xi, The Scientific Research Honor Society
• Member of the Royal Society of Biology (RSB)
• Member of Bergey’s International Society for Microbial Systematics (BISIMiS)
• Member of the International Pangolin Research Consortium (IPaRC)
• Member of the International Pangolin Scientific Advisory Committee
• Member of Pangolin Research Center of China
• Member of The Chinese Society of Biochemistry and Molecular Biology (CSBMB)
• Member of The Chinese Society for Cell Biology (CSCB)
• Member of the Bioinformatics Society of Zhejiang Province
• Member of the Youth Committee of the Bioinformatics Society of Zhejiang Province
• Online Assessment Expert of Eighth Life Science Competition of Zhejiang Province
• Science Technical Committee Member, Wenzhou-Kean University
• Science Technical Committee Member, Liao, Ouhai, Wenzhou
• Member of The Public Speaking Mission of Wenzhou
• Review Editor on the Editorial Board of Plant Proteomics and Protein Structural Biology, Frontiers in Plant Science
• Reviewer for the International Journal of Research and Scientific Innovation (IJRSI)
• Reviewer for Nature Communications
• Reviewer for Frontiers in Microbiology
• Reviewer for Frontiers in Plant Science
• Reviewer for Current Microbiology
• Reviewer for Frontiers in Genetics
• Reviewer for Cancer Medicine

SERVICE：

• Deputy Secretary-General of the Youth Committee of the Bioinformatics Society of Zhejiang Province, 12/2024 to present
• Vice President for Science Education, Liushi High School, Yueqing City, 08/2024 to present
• Associate Director for Wenzhou-Kean University Provincial Biotechnology Experimental Teaching Demonstration Center. 02/2023 to present
• Office Director for Wenzhou Municipal Key Laboratory for Applied Biomedical and Biopharmaceutical Informatics. 09/2021 to present
• Office Director for Zhejiang Bioinformatics International Science and Technology Cooperation Center. 11/2020 to present
• Student representative of Academic Practice Committee, Xi’an Jiaotong Liverpool University, 09/2018 to 09/2019
• Member of the Student-Staff Liaison Committee, Xi’an Jiaotong Liverpool University, 07/2018-08/2018
• Advisor of WKU Science and Technology Club, Wenzhou-Kean University, 2015-2018
• Advisor of Innovation and Entrepreneurship project at WKU, 2017-08/2018
• CLA (Campus Life Advisor), Wenzhou-Kean University, 05/2016-08/2018
• Monitor of Wenzhou University, 09/2011-06/2015
• Training instructors of the first hospital affiliated to Wenzhou Medical University, 2013/2014
• Vice-president of Student Union, Biology division, Wenzhou University, 01/2013-09/2013

Member of the summer social practice team of Qicaihong, Wenzhou University, 06/2012-08/2012

Dr. Tian’s research focuses on the field of life sciences, integrating techniques from cell biology, molecular biology, microbiology, and multi-omics to explore microbial resources, investigate disease mechanisms, and develop therapeutic strategies. The primary research areas include: 1) Utilizing genomic technologies to classify and characterize novel microorganisms from human and environmental sources, screening for highly active and functionally promising strains, and exploring their potential applications in disease therapy. This also involves studying how microorganisms cause infectious diseases through mechanisms such as biofilm formation, revealing their relationships with diseases, and developing targeted intervention strategies; 2) Applying multi-omics approaches to study the dynamics of gut microbiota and their metabolites in the initiation and progression of diseases such as cancer, depression, and autism. This includes validating their roles in disease mechanisms through in vivo and in vitro experiments and exploring the efficacy of natural products and drug combinations as interventions, aiming to evaluate their potential in disease prevention and treatment.

1. Xuechen Tian, Li Chen, Jinfeng Zhou, Enbo Wang, Mu Wang, Nicholas Jakubovics, Jing Li, Kunping Song, King Tong Lau, Klaus-Peter Koepfli, Siyuan Zhang, Geok Yuan Annie Tan, Yixin Yang, Siew Woh Choo. Pangolin scales as adaptations for innate immunity against pathogens. BMC Biology 22, 234 (2024). https://doi.org/10.1186/s12915-024-02034-5. (First author), SCI I Top, Impact Factor (2023): 4.4
2. Xuechen Tian, Wee Fei Aaron Teo, Yixin Yang, Linyinxue Dong, Aloysius Wong, Li Chen, Halah Ahmed, Siew Woh Choo, Nicholas S. Jakubovics, Geok Yuan Annie Tan. Genome characterisation and comparative analysis of Schaalia dentiphila sp. nov. and its subspecies, S. dentiphila subsp. denticola subsp. nov., from the human oral cavity. BMC Microbiology 24, 185 (2024). https://doi.org/10.1186/s12866-024-03346-w. (First author), SCI II, Impact Factor (2023): 4.0
3. Lanni Song, Yixin Yang* and Xuechen Tian*. Current knowledge about immunotherapy resistance for melanoma and potential predictive and prognostic biomarkers. Cancer Drug Resistance. 2024; 7: 17. http://dx.doi.org/10.20517/cdr.2023.150. (*Corresponding Author), Impact Factor: 4.6
4. Siwei Deng, Xuechen Tian, Robert Belshaw, Jinfeng Zhou, Siyuan Zhang, Yixin Yang, Chang Huang, Weikang Chen, Hailu Qiu, Siew Woh Choo. An RNA-Seq analysis of coronavirus in the skin of the Pangolin. Scientific Reports 14, 910 (2024). https://doi.org/10.1038/s41598-024-51261-x. SCI II, Impact Factor (2022): 4.6
5. Lanxing Li, Linyinxue Dong, Xuechen Tian, Yusef Kianpoor Kalkhajeh, Yixin Yang & Samuel Ken-En Gan. Optimizing the ratio of coomassie and methylene blue dyes for a cost-effective and rapid staining of PET, PVC, PP, PS, LLDPE, LDPE, and HDPE. Discover Sustainability 5, 74 (2024). https://doi.org/10.1007/s43621-024-00261-y. Impact Factor (2022): 2.6.
6. Xuechen Tian, Wee Fei Aaron Teo, Wei Yee Wee, Yixin Yang, Halah Ahmed, Nicholas S. Jakubovics, Siew Woh Choo, Geok Yuan Annie Tan. Genome characterization and taxonomy of Actinomyces acetigenes sp. nov., and Actinomyces stomatis sp. nov., previously isolated from the human oral cavity. BMC Genomics 24, 734 (2023). https://doi.org/10.1186/s12864-023-09831-2. (First Author), SCI II Top, Impact Factor (2022): 4.4
7. Kunping Song, Li Chen, Nanhua Suo, Xinyi Kong, Juexi Li, Tianyu Wang, Lanni Song, Mengwei Cheng, Xindian Guo, Zhenghe Huang, Zichen Huang, Yixin Yang, Xuechen Tian* and Siew Woh Choo*. Whole-transcriptome analysis reveals mechanisms underlying antibacterial activity and biofilm inhibition by a malic acid combination (MAC) in Pseudomonas aeruginosa. PeerJ (2023). 11:e16476 http://doi.org/10.7717/peerj.16476. (*Corresponding Author), SCI III, Impact Factor (2022): 2.7
8. Lanni Song, Chen Li, Jia Yu, Xuechen Tian* and Siew Woh Choo*. The anti-cancer effect and mechanism of animal scale-derived extract on malignant melanoma cells. Scientific Reports 13, 12548 (2023). https://doi.org/10.1038/s41598-023-39742-x. (*Corresponding Author), SCI II, Impact Factor (2022): 4.6
9. Aloysius Wong, Wei Chi, Jia Yu, Chuyun Bi, Xuechen Tian, Yixin Yang & Chris Gehring. Plant adenylate cyclases have come full circle. Nature Plants (2023). https://doi.org/10.1038/s41477-023-01486-x. SCI I Top, Impact Factor (2022): 18
10. Jiaqi Zhang, Yuxin Deng, Yuewen Fang, Ming Xie, Jia Yu, Siew Woh Choo* and Xuechen Tian*. Transcriptomic Profiling Reveals the Underlying Mechanism of Interferon-Epsilon (IFN-ε) and Interferon-Gamma (IFN-γ) Combination in Cervical Cancer. Biomedical Journal of Scientific & Technical Research 54(1)-2023. BJSTR. MS.ID.008510. 10.26717/BJSTR.2023.54.008510. (*Corresponding Author).
11. Xuechen Tian, Zixin Rong, Siew Woh Choo. Transcriptomic Profiling Reveals the Novel Role and Mechanism of Interferon-Epsilon (IFN-Ɛ) on Human Melanoma. Chronicles of Oncology. 2023; 6(2): 1013. (First Author).
12. Linyinxue Dong, Ceeane Paul Dagoc Vargas, Xuechen Tian, Xiayu Chu, Chenqi Yin, Aloysius Wong and Yixin Yang*. Harnessing the Potential of Non-Apoptotic Cell Death Processes in the Treatment of Drug-Resistant Melanoma. International Journal of Molecular Sciences. 2023; 24(12):10376. https://doi.org/10.3390/ijms241210376. SCI II, Impact Factor (2022): 5.6
13. Dong, Linyinxue^†, Xuechen Tian^†, Yunqi Zhao, Haohong Tu, Aloysius Wong, and Yixin Yang. 2022. The Roles of MiRNAs (MicroRNAs) in Melanoma Immunotherapy. International Journal of Molecular Sciences. 23, no. 23: 14775. https://doi.org/10.3390/ijms232314775. (^†Co-first author), SCI II, Impact Factor (2021): 6.2
14. Aloysius Wong, Xuechen Tian, Yixin Yang, Chris Gehring. (2022). Adenylate cyclase activity of TIR1/AFB links cAMP to auxin-dependent responses. Molecular. Plant. doi: https://doi.org/10.1016/j.molp.2022.11.012. SCI I Top, Impact Factor (2021): 27.5
15. Shiyu Jiang, Hemn Barzan Abdalla, Chuyun Bi, Yi Zhu, Xuechen Tian, Yixin Yang, Aloysius Wong, HNOXPred: a web tool for the prediction of gas sensing H-NOX proteins from amino acid sequence, Bioinformatics, 2022;, btac571, https://doi.org/10.1093/bioinformatics/btac571. SCI III, Impact Factor (2021): 6.9
16. Wanying Dou, Hemn Barzan Abdalla, Xu Chen, Changyi Sun, Xuefei Chen, Qiwen Tian, Junyi Wang, Wei Zhou, Wei Chi, Xuan Zhou, Hailv Ye, Chuyun Bi, Xuechen Tian, Yixin Yang, Aloysius Wong, ProbResist: a database for drug-resistant probiotic bacteria, Database, Volume 2022, 2022, baac064, https://doi.org/10.1093/database/baac064. SCI IV, Impact Factor (2021): 4.5
17. Siew Woh Choo, Xuechen Tian, et al. A collective statement in support of saving pangolins, Science of The Total Environment, Volume 824, 2022, 153666, ISSN 0048-9697, https://doi.org/10.1016/j.scitotenv.2022.153666. SCI I Top, Impact Factor (2021): 10.7
18. Yi Wang, Jingya Dong, Junyi Wang, Wei Chi, Wei Zhou, Qiwen Tian, Yue Hong, Xuan Zhou, Hailv Ye, Xuechen Tian, Rongdang Hu & Aloysius Wong (2022) Assessing the drug resistance profiles of oral probiotic lozenges, Journal of Oral Microbiology, 14:1,DOI: 10.1080/20002297.2021.2019992. SCI II, Impact Factor (2020): 5.5
19. Aloysius Wong, Ningxin Hu, Xuechen Tian, Yixin Yang, Christoph Gehring. Nitric oxide sensing revisited. Trends in Plant Science. 2021. ISSN 1360-1385, https://doi.org/10.1016/j.tplants.2021.03.009. SCI I Top, Impact Factor (2020): 18.3
20. Wei Zhou, Wei Chi, Wanting Shen, Wanying Dou, Junyi Wang, Xuechen Tian, Christoph Gehring and Aloysius Wong*. Computational Identification of Functional Centers in Complex Proteins: A Step-by-Step Guide With Examples. Frontiers in Bioinformatics. 2021. Volume 1, Pages 5. DOI:10.3389/fbinf.2021.652286.
21. Aloysius Wong, Xuechen Tian, Yixin Yang, Christoph Gehring. Identification of potential nitric oxide-sensing proteins using the H-NOX motif. Molecular Plant. 2021 Feb 1; Volume 14, Issue 2, Pages 195-197. https://doi.org/10.1016/j.molp.2020.11.015. SCI I Top, Impact Factor (2020): 13.2
22. Siew Woh Choo, Jinfeng Zhou, Xuechen Tian, Siyuan Zhang, Qiang Shen, Stephen J. O'Brien, Ka Yun Tan, Sara Platto, Klaus-Peter Koepfli, Agostinho Antunes, Frankie Thomas Sitam. Are pangolins scapegoats of the COVID-19 outbreak- CoV transmission and pathology evidence? Conservation Letters. 2020;e12754. https://doi.org/10.1111/conl.12754. SCI I, Impact Factor (2019): 6.8
23. Claudius Marondedze, Xinyun Liu, Shihui Huang, Cynthia Wong, Xuan Zhou, Xutong Pan, Huiting An, Nuo Xu, Xuechen Tian and Aloysius Wong. Towards a tailored indoor horticulture: a functional genomics guided phenotypic approach. Horticulture Research (2018) 5:68 DOI 10.1038/s41438-018-0065-7. SCI I Top, Impact Factor (2018): 3.4
24. Toby M. Michelena, Xuechen Tian, Xuan Zhou and Yu Meng. The impact on the activity of acetylcholinesterase of a polylysine-ApoE peptide carrier targeting the blood brain barrier. Fundamental Toxicological Sciences (Fundam. Toxicol. Sci.).Vol.5, No.4, 123-126, 2018.
25. Aloysius Wong, Xuechen Tian, Chris Gehring, Claudius Marondedze. Discovery of Novel Functional Centers With Rationally Designed Amino Acid Motifs: Computational and Structural Biotechnology Journal 16 (2018) 70–76. SCI II, Impact Factor (2018): 4.1
26. Min Zheng, Ruijia Zhang, Xuechen Tian, Xuan Zhou, Xutong Pan and Aloysius Wong*. Assessing the risk of probiotic dietary supplements in the context of antibiotic resistance: Frontiers Microbiology, Vol.8.908. May 19 2017. SCI II Top, Impact Factor (2016): 4.1