戴利雄,博士

  • 职位:
    研究生导师
  • 学院:
    理工学院

Biography

戴利雄,2020年4月加入中国科学院大学温州研究院任岗位研究员,中国稀土学会稀土分子材料与超分子器件专业委员会委员。2007年本科毕业于湖南科技大学,之后在上市医药公司从事5年药物小分子研发。2012年到2020年于香港浸会大学、香港理工大学学习工作(师从黄嘉良教授、罗嘉丽教授及黄永德教授)。主要从事镧系金属配合物的研究,其中开发的手性大环类配体及配合物在磁共振成像、光学分子成像及放射诊疗中的应用前景广泛。近5年在Nat.Commun.、Angew. Chem., Int. Ed.、Chem. Sci.、Inorg. Chem.等学术期刊上发表学术论文并申请PCT专利。主持浙江省自然科学基金重点项目、国家自然科学基金面上项目、中国科学院大学温州研究院重大项目。

Education

  1. 05/2014-04/2017: PhD (Inorganic Biochemistry), Department of Chemistry, Hong Kong Baptist University, Hong Kong, China
  2. 09/2003-06/2007: BSc (Applied Chemistry), Department of Chemistry and Chemical Engineering, Hunan University of Science and Technology, China

Academic Experience

  1. 04/2020-present: Associate Professor, Wenzhou institute, University of Chinese Academy of Sciences, Wenzhou, China
  2. 05/2017-04/2020: Postdoctoral Fellow, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
  3. 09/2007-10/2012: Organic / Pharmaceutical Synthesis, Pharmaron, Beijing, China

Research Interests

  1. Developmentofmore efficient and safer MRI contrast agents
  2. Development of more efficient radiometal chelators for radioimmunotherapy
  3. Synthesis of luminescent lanthanide materials for bio-imaging
  4. Synthesis of chiral lanthanide complexes for circularly polarized luminescence (CPL) applications

Selected Research Publications

  1. Dai, L.; Jones, C.M.; Chan, T-K.; Pham, T.A.; Ling, X.; Gale, E.M.; Rotile, N.J.; Tai, C.-S.; Anderson, C.J.; Caravan, P.; Law, G.-L.,Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications. Nature Communications 2018, 9 (1), 857.
  2. Dai, L.; Lo, W.-S.; Gu, Y.; Xiong, Q.; Wong, K.-L.; Kwok, W.-M.; Wong, W.-T.; Law, G.-L. Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(III) luminescence and unprecedented two-photon excitation properties. Chemical Science 2019,10 (17), 4550. (inside cover,hot article)
  3. Dai, L.; Zhang, J.; Chen, Y.; Lewis, M.; Pal, R.; Law, G.-L. Synthesis of Water-soluble Chiral DOTA Lanthanide Complexes with Predominantly Twisted Square Antiprism Isomers& CPL Emission.Inorganic Chemistry 201958, 12506-12510
  4. Dai, L.; Lo, W.-S.; Zhang, J.; Law, G.-L., One-Step Reaction for Screening of Chromophores to Improve the Luminescence of Lanthanide Complexes. Asian Journal of Organic Chemistry 2017,6 (12), 1845-1850.
  5. Dai, L.; Lo, W.-S.; Coates, I. D.; Pal, R.; Law, G.-L., New Class of Bright and Highly Stable Chiral Cyclen Europium Complexes for Circularly Polarized Luminescence Applications. Inorganic Chemistry 2016, 55 (17), 9065-9070.
  6. Zhang, J.; Dai, L.; Webster, A.M.; Chan, W.T.K.; Mackenzie, L.; Pal, R.; Cobb, S.L.; and Law, G.-L., Unusual Magnetic Field Responsive Circularly Polarized Luminescence Probes with Highly Emissive Chiral Eu(III) Complexes. Angewandte Chemie-International Edition2020, ASAP. doi:10.1002/anie.202012133.