戴利雄,博士
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职位:研究生导师
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学院:理工学院
Biography
戴利雄,2020年4月加入中国科学院大学温州研究院任岗位研究员,中国稀土学会稀土分子材料与超分子器件专业委员会委员。2007年本科毕业于湖南科技大学,之后在上市医药公司从事5年药物小分子研发。2012年到2020年于香港浸会大学、香港理工大学学习工作(师从黄嘉良教授、罗嘉丽教授及黄永德教授)。主要从事镧系金属配合物的研究,其中开发的手性大环类配体及配合物在磁共振成像、光学分子成像及放射诊疗中的应用前景广泛。近5年在Nat.Commun.、Angew. Chem., Int. Ed.、Chem. Sci.、Inorg. Chem.等学术期刊上发表学术论文并申请PCT专利。主持浙江省自然科学基金重点项目、国家自然科学基金面上项目、中国科学院大学温州研究院重大项目。
Education
- 05/2014-04/2017: PhD (Inorganic Biochemistry), Department of Chemistry, Hong Kong Baptist University, Hong Kong, China
- 09/2003-06/2007: BSc (Applied Chemistry), Department of Chemistry and Chemical Engineering, Hunan University of Science and Technology, China
Academic Experience
- 04/2020-present: Associate Professor, Wenzhou institute, University of Chinese Academy of Sciences, Wenzhou, China
- 05/2017-04/2020: Postdoctoral Fellow, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
- 09/2007-10/2012: Organic / Pharmaceutical Synthesis, Pharmaron, Beijing, China
Research Interests
- Developmentofmore efficient and safer MRI contrast agents
- Development of more efficient radiometal chelators for radioimmunotherapy
- Synthesis of luminescent lanthanide materials for bio-imaging
- Synthesis of chiral lanthanide complexes for circularly polarized luminescence (CPL) applications
Selected Research Publications
- Dai, L.; Jones, C.M.; Chan, T-K.; Pham, T.A.; Ling, X.; Gale, E.M.; Rotile, N.J.; Tai, C.-S.; Anderson, C.J.; Caravan, P.; Law, G.-L.,Chiral DOTA chelators as an improved platform for biomedical imaging and therapy applications. Nature Communications 2018, 9 (1), 857.
- Dai, L.; Lo, W.-S.; Gu, Y.; Xiong, Q.; Wong, K.-L.; Kwok, W.-M.; Wong, W.-T.; Law, G.-L. Breaking the 1,2-HOPO barrier with a cyclen backbone for more efficient sensitization of Eu(III) luminescence and unprecedented two-photon excitation properties. Chemical Science 2019,10 (17), 4550. (inside cover,hot article)
- Dai, L.; Zhang, J.; Chen, Y.; Lewis, M.; Pal, R.; Law, G.-L. Synthesis of Water-soluble Chiral DOTA Lanthanide Complexes with Predominantly Twisted Square Antiprism Isomers& CPL Emission.Inorganic Chemistry 2019, 58, 12506-12510
- Dai, L.; Lo, W.-S.; Zhang, J.; Law, G.-L., One-Step Reaction for Screening of Chromophores to Improve the Luminescence of Lanthanide Complexes. Asian Journal of Organic Chemistry 2017,6 (12), 1845-1850.
- Dai, L.; Lo, W.-S.; Coates, I. D.; Pal, R.; Law, G.-L., New Class of Bright and Highly Stable Chiral Cyclen Europium Complexes for Circularly Polarized Luminescence Applications. Inorganic Chemistry 2016, 55 (17), 9065-9070.
- Zhang, J.; Dai, L.; Webster, A.M.; Chan, W.T.K.; Mackenzie, L.; Pal, R.; Cobb, S.L.; and Law, G.-L., Unusual Magnetic Field Responsive Circularly Polarized Luminescence Probes with Highly Emissive Chiral Eu(III) Complexes. Angewandte Chemie-International Edition2020, ASAP. doi:10.1002/anie.202012133.